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- Eduardo Gonzalez-Couto, Silvia Matteoni, Stefano Gotta, Letizia Magnoni, Freddy Heitz, Roberto Raggiaschi, Georg C Terstappen and Andreas Kremer
Huntington's disease: from experimental results to interaction networks, patho-pathway construction and disease hypothesis
BMC Systems Biology 2007;1 Suppl 1:P45.
 (click to download)
- Semeraro T., Lossani A., Botta M., Ghiron C., Alvarez R., Manetti F., Mugnaini C. Valensis S., Focher F., Corelli F.
"Simplified analogues of immucillin-g retain potent human purine nucleoside phosphorylase inhibitory activity" J Med Chem.; 49(20):6037-45
- Kremer A.
"Huntington's Disease: From Information to Pathway & Interaction Networks" European HD Network meeting, Blankenberge, Belgium
- Scali C., Caraci F., Gianfriddo M., Diodato E., Roncarati R., Pollio G., Gaviraghi G., Copani A., Nicoletti F., Terstappen GC., Caricasole A.
"Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1" Neurobiol Dis.
- Caruso A., Motolese M., Iacovelli L., Caraci F., Copani A., Nicoletti F., Terstappen GC., Gaviraghi G., Caricasole A.
"Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells" J Neurochem; 98(2):364-71
- Porcari V.
"Biochemical and cellular screening approaches for the identification of BACE1 inhibitors" IBC Life Sciences, target seminars (proteases, kinases), Berlin, Germany
- Giovanni Gaviraghi, Goran Westerberg, Graeme Robertson
"Functional imaging as a tool to validate PK/PD profiles and predict individual sensitivity to CNS drugs" Biological Basis of Individual Sensitivity to Psychotropic Drugs, Moscow
- Kremer A.
"A Bioinformatics Perspective on Proteomics: "Identification, Data Storage, Analysis and Integration"". Siemens PSE Life Science Symposium, Brno, Czech Rep.
- Scheib H., McLay I., Guex N., Clare J.J., Blaney F.E., Dale T.J., Tate S.N. and Robertson G.M.
"Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformarion reveals details of site 1 toxin and local anesthetic binding" J Mol Model (Online)
- Raggiaschi R., Lorenzetto C., Diodato E., Caricasole A., Gotta S., Terstappen GC.
"Detection of phosphorylation patterns in rat cortical neurons by combining phosphatase treatment and DIGE technology" Proteomics; 6(3):748-56
- Terstappen GC., Gaviraghi G., Caricasole A.
"The Wnt signaling pathway as a target for the treatment of neurodegenerative disorders" IDrigs.; 9(1):35-8. PMID: 16374731
- Caricasole A., Bakker A., Copani A., Nicoletti F., Gaviraghi G, Terstappen GC.
"Two ides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology" Biosci Rep.; 25(5-6):309-27. Review
- Ghiron C.
"The use of scavenger resins in the synthesis and purification of organic molecules". Seminars in Organic Synthesis, Summer School "A. Corbella", 30th, Gargano, Italy, 139-162
- Kremer A.
"Bioinformatics in drug discovery" Corso di Laurea in Biotecnologie Industriali e Ambientali, Milano, Italy
- Raggiaschi R., Gotta S., Terstappen GC.
"Phosphoproteome analysis" Biosci Rep.; 25(1-2)33-44. Review
- Kremer A., Schenider R., Terstappen GC.
"A bioinformatics perspective on proteomics: data storage, analysis, and integration" Biosci Rep.; 25(1-2):95-106. Review
- Porcari V., Magnoni L., Terstappen G.C., Fecke W.
"A continuous time-resolved fluorescence assay for identification of BACE1 inhibitors", ASSAY and Drug Development Technologies, 3, 287-97
- Caricasole, A., Bakker, A., Copani, A., Gaviraghi, G., Nicoletti, F. and Terstappen, G. C. (2005)
Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology, Bioscience Reports 25, 309-327
- Roncarati, R., Decimo, I., Fumagalli, G.
Assembly and trafficking of human small conductance Ca(2+)-activated K(+) channel SK3 are governed by different molecular domains." Mol Cell Neurosci. 28, 314-25 (2005)
- Raggiaschi, R., Lorenzetto, C., Diodato, E., Caricasole, A., Gotta, S. and Terstappen, G. C. (2005)
Detection of phosphorylation patterns in rat cortical neurons by combining phosphatase treatment and DIGE technology, Proteomics, Dec 21 [Epub ahead of print]
- Ghiron C., Nannetti L., Taddei M.
"Alkene epoxidation with urea-hydrogen peroxide complex and PS-DVB supported phthalic anhydride" Tetrahedron Letters, 46(10), 1643-1645
- Terstappen, G. C., Gaviraghi, G. and Caricasole, A. (2006)
The Wnt signaling pathway as a target for treatment of neurodegenerative disorders, IDrugs 9, 35-8
- Kremer, A., Schneider, R. and Terstappen, G. C. (2005)
A bioinformatics perspective on proteomics: data storage, analysis, and integration, Bioscience Reports 25, 95-106
- Raggiaschi R., Gotta S. and Terstappen G. C. (2005)
Phosphoproteome analysis, Bioscience Reports 25, 33-44
(click to download)
- Raggiaschi, R. and Terstappen G. C. (eds.) (2005)
Proteomics technologies, Bioscience Reports 25, (Nos. 1-2)
- Terstappen, G. C. (2005)
Ion channel screening technologies today, Drug Discovery Today: Technologies 2, 133-140
- Porcari, V., Magnoni, L., Terstappen, G. C. and Fecke, W. (2005)
A Continuous Time Resolved Fluorescence Assay for Identification of BACE1 Inhibitors, Assay and Drug Development Technologies 3, 287-297
- Ghiron, C., Nannetti, L., Taddei, M. (2005)
Alkene epoxidation with urea-hydrogen peroxide complex and PS-DVB supported phthalic anhydride, Tetrahedron Letters 46, 1643-1645
- Cappuccio, I., Busceti, L., Biagioni, F., Pontarelli, F., Bruno, V., Storto, M., Calderone, A., Terstappen, G. C. , Gaviraghi, G., Fornai, F., Battaglia, F., Melchiorri, D., Zukin, S., Nicoletti, F. and Caricasole, A. (2005)
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the induction of ischemic neuronal death, J. Neuroscience 25, 2647-2657
- Otrocka M.
"Measuring small amounts of secreted proteins in primary rat cell culture". IBC conference on assay development, Amsterdam, Netherlands
- Terstappen GC.
"Nonradioactive rubidium ion efflux assay and its applications in drug discovery and development" Assay Drug Dev Technol.
- Caricasole, A., Copani, A., Caraci, F., Aronica, E., Rozemuller, A., Caruso, A., Storto, M., Gaviraghi, G., Terstappen, G. C. and Nicoletti, F. (2004)
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer’s brain, J. Neuroscience 24, 6021-6027
(click to download)
- Terstappen G.C.
"Nonradioactive Rubidium Ion Efflux Assay and Its Applications in Drug Discovery and Development" ASSAY and Drug Development Technologies, 2(5), 553-559
(click to download)
- Terstappen G.C.
"Ion channel drug discovery using nonradioactive Rb efflux assay" International conference on cell-based assay technologies, Cologne, Germany
- Terstappen G. C.
"Emerging technologies inion channel drug discovery" International Ion channel retreat, Whistler, Canada
- Terstappen G.C., Pellacani A., Aldegheri L., Graziani F., Carignani C., Pula G., and Virginio C.
"The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3" Neuroscience Lett. 346, 85-8
- Carbonelle E. Sparatore F., Canu-Boido F., Salvagno C., Baldani-Guerra B., Terstappen G.C., Zwart R., Vijverberg H.P.M., Clementi F. and Gotti C.
"Nitrogen substitution modifies the activity of cytosine on neuronal nicotinic receptor subtypes" Eur. J. Pharmacol. 471, 85-96
- Caricasole, A., Copani, A., Caruso, A., Caraci, F., Iacovelli, L., Sortino, M. A., Terstappen, G. C. and Nicoletti, F. (2003)
The Wnt pathway, cell-cycle activation and β-amyloid: novel therapeutic strategies in Alzheimer’s disease?, Trends Pharmacol. Sci. 24, 233-238
(click to download)
- Caricasole, A., Ferraro, T., Iacovelli, L., Barletta, E., Caruso, A., Melchiorri, D., Terstappen G. C. and Nicoletti F. (2003)
Functional characterization of Wnt 7a signalling in PC12 cells: Interaction with a FZD5/LRP6 receptor complex and modulation by DKK proteins, J. Biol. Chem. 278, 37024-37031
(click to download)
- Roncarati R., Decimo I. and Fumagalli G.
"Assembly and trafficking of human small condictance calcium-activated potassium channel SK3 is governed by different molecular domains". Mol. Cell. Neurosci. (in press)
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