Proteins are the major constituent of a cell and regulate all functional processes occurring inside an organism.

Thus, understanding the processes and underlying causes of human disease require information about protein functions and how and if such functionality has been altered or disrupted.

The analysis and detection of protein cell components are carried out using a plethora of proteomics techniques including classical 2D gel electrophoresis, 2D immunoblotting, and ESI mass spectrometry for protein identification. Moreover, DIGE (differential in gel electrophoresis) technology and electrospray mass spectrometry in a 2D nano LC/MS/MS configuration are key technologies routinely applied for the detection of differentially expressed or post-translational modified proteins.

All of these technologies are employed to identify novel potential drug targets and/or validate protein targets involved in the pathogenesis of neurodegenerative and proliferative diseases.

In addition, bacterial, mammalian and insect expression systems are used to produce functional proteins as research reagents necessary for assay development purposes.