Cancer is the result of a group of events that induce aberrations in proliferation, motility and invasion characteristics of cells. It can originate almost anywhere in the body. Nervous system neoplasms are relatively rare diseases whose disabling effects are out of proportion to their incidence.

Cancer Biology at Siena Biotech is committed to the discovery of treatments to cure both glial tumors and medulloblastoma. To this end, the identification and validation of novel targets known to be involved in a wide range of neuro-oncology relevant pathways is an important part of research.

In addition, a comprehensive panel of functional cell-based assays are developed and employed to monitor the effect of compounds on targets which are implied in neuro-oncology-relevant signal transduction pathways. In strong collaboration with other parts of research, these activities should lead to new treatments of brain cancer.